Loss of NKG2D in murine NK cells leads to increased perforin production upon long‐term stimulation with IL‐2

NK cells are innate lymphocytes responsible for lysis of pathogen‐infected and transformed cells. One of the major activating receptors required for target cell recognition is the NK group 2D (NKG2D) receptor. Numerous reports show the necessity of NKG2D for effective tumor immune surveillance. Furt...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Prinz, Daniela, Klein, Klara, List, Julia, Knab, Vanessa M., Menzl, Ingeborg, Leidenfrost, Nicoletta, Heller, Gerwin, Polić, Bojan, Putz, Eva Maria, Witalisz‐Siepracka, Agnieszka, Sexl, Veronika, Gotthardt, Dagmar
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Tumor immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318224/
https://ncbi.nlm.nih.gov/pubmed/32052406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948222
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