Loss of NKG2D in murine NK cells leads to increased perforin production upon long‐term stimulation with IL‐2

NK cells are innate lymphocytes responsible for lysis of pathogen‐infected and transformed cells. One of the major activating receptors required for target cell recognition is the NK group 2D (NKG2D) receptor. Numerous reports show the necessity of NKG2D for effective tumor immune surveillance. Furt...

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Detaylı Bibliyografya
Yayımlandı:Eur J Immunol
Asıl Yazarlar: Prinz, Daniela, Klein, Klara, List, Julia, Knab, Vanessa M., Menzl, Ingeborg, Leidenfrost, Nicoletta, Heller, Gerwin, Polić, Bojan, Putz, Eva Maria, Witalisz‐Siepracka, Agnieszka, Sexl, Veronika, Gotthardt, Dagmar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Tumor immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318224/
https://ncbi.nlm.nih.gov/pubmed/32052406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948222
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