Loss of JAK1 Drives Innate Immune Deficiency

The Janus kinase—signal transducers and activators of transcription (JAK-STAT) signaling pathway is critical in tuning immune responses and its dysregulation is tightly associated with cancer and immune disorders. Disruption of interleukin (IL)-15/STAT5 signaling pathway due to the loss of IL-15 rec...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Immunol
Prif Awduron: Witalisz-Siepracka, Agnieszka, Klein, Klara, Prinz, Daniela, Leidenfrost, Nicoletta, Schabbauer, Gernot, Dohnal, Alexander, Sexl, Veronika
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2019
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331462/
https://ncbi.nlm.nih.gov/pubmed/30671064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03108
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