Dihydrosphingosine driven enrichment of sphingolipids attenuates TGFβ induced collagen synthesis in cardiac fibroblasts

The sphingolipid de novo synthesis pathway, encompassing the sphingolipids, the enzymes and the cell membrane receptors, are being investigated for their role in diseases and as potential therapeutic targets. The intermediate sphingolipids such as dihydrosphingosine (dhSph) and sphingosine (Sph) hav...

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Vydáno v:Int J Cardiol Heart Vasc
Hlavní autoři: Magaye, Ruth R., Savira, Feby, Xiong, Xin, Huynh, Kevin, Meikle, Peter J., Reid, Christopher, Flynn, Bernard L., Kaye, David, Liew, Danny, Wang, Bing H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264607/
https://ncbi.nlm.nih.gov/pubmed/34277924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcha.2021.100837
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