Dihydrosphingosine driven enrichment of sphingolipids attenuates TGFβ induced collagen synthesis in cardiac fibroblasts

The sphingolipid de novo synthesis pathway, encompassing the sphingolipids, the enzymes and the cell membrane receptors, are being investigated for their role in diseases and as potential therapeutic targets. The intermediate sphingolipids such as dihydrosphingosine (dhSph) and sphingosine (Sph) hav...

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Detalhes bibliográficos
Publicado no:Int J Cardiol Heart Vasc
Main Authors: Magaye, Ruth R., Savira, Feby, Xiong, Xin, Huynh, Kevin, Meikle, Peter J., Reid, Christopher, Flynn, Bernard L., Kaye, David, Liew, Danny, Wang, Bing H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264607/
https://ncbi.nlm.nih.gov/pubmed/34277924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcha.2021.100837
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