Matrix metalloproteinase-9 activates TGF-β and stimulates fibroblast contraction of collagen gels

Matrix metalloproteinase-9 (MMP-9) is a matrix-degrading enzyme implicated in many biological processes, including inflammation. It is produced by many cells, including fibroblasts. When cultured in three-dimensional (3D) collagen gels, fibroblasts contract the surrounding matrix, a function that is...

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Main Authors: Kobayashi, Tetsu, Kim, HuiJung, Liu, Xiangde, Sugiura, Hisatoshi, Kohyama, Tadashi, Fang, Qiuhong, Wen, Fu-Qiang, Abe, Shinji, Wang, Xingqi, Atkinson, Jeffrey J., Shipley, James M., Senior, Robert M., Rennard, Stephen I.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042193/
https://ncbi.nlm.nih.gov/pubmed/24705725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00015.2014
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