Tranilast inhibits TGF-β-induced collagen gel contraction mediated by human corneal fibroblasts

AIM: To determine if tranilast affects human corneal fibroblast (HCFs) contraction. METHODS: HCFs cultured in a three-dimensional type I collagen gel were treated with or without transforming growth factor beta (TGF-β) or tranilast. Gel diameter was measured as an indicator for collagen contraction....

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Detalhes bibliográficos
Publicado no:Int J Ophthalmol
Main Authors: Liu, Ye, Zhao, Xiao-Jing, Zheng, Xiao-Shuo, Zheng, Hui, Liu, Lei, Meng, Ling-Bin, Li, Qin, Liu, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: International Journal of Ophthalmology Press 2018
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090117/
https://ncbi.nlm.nih.gov/pubmed/30140625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2018.08.01
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