In vivo / in vitro Correlation of Pharmacokinetics of Gentamicin, Vancomycin, Teicoplanin and Doripenem in a Bovine Blood Hemodialysis Model

Background: Elimination of a drug during renal replacement therapy is not only dependent on flow rates, molecular size and protein binding, but is often influenced by difficult to predict drug membrane interactions. In vitro models allow for extensive profiling of drug clearance using a wide array o...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Vossen, M G, Pferschy, S, Milacek, C, Haidinger, M, Karolyi, Mario, Vass, Zoltan, Burgmann, Heinz, Maier-Salamon, Alexandra, Wicha, S G, Jäger, W, Zeitlinger, M, Stimpfl, T, Wittek, T, Thalhammer, F
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264131/
https://ncbi.nlm.nih.gov/pubmed/34248646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.702455
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