In vivo / in vitro Correlation of Pharmacokinetics of Gentamicin, Vancomycin, Teicoplanin and Doripenem in a Bovine Blood Hemodialysis Model

Background: Elimination of a drug during renal replacement therapy is not only dependent on flow rates, molecular size and protein binding, but is often influenced by difficult to predict drug membrane interactions. In vitro models allow for extensive profiling of drug clearance using a wide array o...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Vossen, M G, Pferschy, S, Milacek, C, Haidinger, M, Karolyi, Mario, Vass, Zoltan, Burgmann, Heinz, Maier-Salamon, Alexandra, Wicha, S G, Jäger, W, Zeitlinger, M, Stimpfl, T, Wittek, T, Thalhammer, F
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264131/
https://ncbi.nlm.nih.gov/pubmed/34248646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.702455
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