In vivo / in vitro Correlation of Pharmacokinetics of Gentamicin, Vancomycin, Teicoplanin and Doripenem in a Bovine Blood Hemodialysis Model

Background: Elimination of a drug during renal replacement therapy is not only dependent on flow rates, molecular size and protein binding, but is often influenced by difficult to predict drug membrane interactions. In vitro models allow for extensive profiling of drug clearance using a wide array o...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Vossen, M G, Pferschy, S, Milacek, C, Haidinger, M, Karolyi, Mario, Vass, Zoltan, Burgmann, Heinz, Maier-Salamon, Alexandra, Wicha, S G, Jäger, W, Zeitlinger, M, Stimpfl, T, Wittek, T, Thalhammer, F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264131/
https://ncbi.nlm.nih.gov/pubmed/34248646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.702455
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