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A comparative study of Bayesian optimal interval (BOIN) design with interval 3+3 (i3+3) design for phase I oncology dose-finding trials
Bayesian optimal interval (BOIN) design is a model-assisted phase I dose-finding design to find the maximum tolerated dose (MTD). The hallmark of the BOIN design is its concise decision rule — making the decision of dose escalation and de-escalation by simply comparing the observed dose-limiting tox...
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| Publicado no: | Stat Biopharm Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8261789/ https://ncbi.nlm.nih.gov/pubmed/34249223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19466315.2020.1811147 |
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