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Small changes in the length of diselenide bond-containing linkages exert great influences on the antitumor activity of docetaxel homodimeric prodrug nanoassemblies
Homodimeric prodrug-based self-assembled nanoparticles, with carrier-free structure and ultrahigh drug loading, is drawing more and more attentions. Homodimeric prodrugs are composed of two drug molecules and a pivotal linkage. The influence of the linkages on the self-assembly, in vivo fate and ant...
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| Publié dans: | Asian J Pharm Sci |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Shenyang Pharmaceutical University
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8261084/ https://ncbi.nlm.nih.gov/pubmed/34276822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2021.02.002 |
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