Probing the fluorination effect on the self-assembly characteristics, in vivo fate and antitumor efficacy of paclitaxel prodrug nanoassemblies

Rationale: Small-molecule prodrug nanoassembly is emerging as an efficient platform for chemotherapy. The self-assembly stability plays a vital role on the drug delivery efficiency of prodrug nanoassembly. It is reported that fluoroalkylation could improve the self-assembly stability of amphiphilic...

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Bibliographic Details
Published in:Theranostics
Main Authors: Wang, Xin, Yang, Bin, Li, Lingxiao, Liu, Tian, Zuo, Shiyi, Chi, Dongxu, He, Zhonggui, Sun, Bingjun, Sun, Jin
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2021
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315070/
https://ncbi.nlm.nih.gov/pubmed/34335971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.61337
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