DNA polymerase λ promotes error-free replication through Watson–Crick impairing N1-methyl-deoxyadenosine adduct in conjunction with DNA polymerase ζ

In a previous study, we showed that replication through the N1-methyl-deoxyadenosine (1-MeA) adduct in human cells is mediated via three different Polι/Polθ, Polη, and Polζ-dependent pathways. Based on biochemical studies with these Pols, in the Polι/Polθ pathway, we inferred a role for Polι in the...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Yoon, Jung-Hoon, Basu, Debashree, Choudhury, Jayati Roy, Prakash, Satya, Prakash, Louise
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260881/
https://ncbi.nlm.nih.gov/pubmed/34119520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100868
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