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Evidence for a Watson-Crick Hydrogen Bonding Requirement in DNA Synthesis by Human DNA Polymerase κ

The efficiency and fidelity of nucleotide incorporation by high-fidelity replicative DNA polymerases (Pols) are governed by the geometric constraints imposed upon the nascent base pair by the active site. Consequently, these polymerases can efficiently and accurately replicate through the template b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wolfle, William T., Washington, M. Todd, Kool, Eric T., Spratt, Thomas E., Helquist, Sandra A., Prakash, Louise, Prakash, Satya
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190260/
https://ncbi.nlm.nih.gov/pubmed/16055723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7137-7143.2005
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