Evidence for a Watson-Crick Hydrogen Bonding Requirement in DNA Synthesis by Human DNA Polymerase κ

The efficiency and fidelity of nucleotide incorporation by high-fidelity replicative DNA polymerases (Pols) are governed by the geometric constraints imposed upon the nascent base pair by the active site. Consequently, these polymerases can efficiently and accurately replicate through the template b...

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Detalhes bibliográficos
Main Authors: Wolfle, William T., Washington, M. Todd, Kool, Eric T., Spratt, Thomas E., Helquist, Sandra A., Prakash, Louise, Prakash, Satya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Chromosome Structure and Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190260/
https://ncbi.nlm.nih.gov/pubmed/16055723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7137-7143.2005
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