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A novel role of DNA polymerase λ in translesion synthesis in conjunction with DNA polymerase ζ
By extending synthesis opposite from a diverse array of DNA lesions, DNA polymerase (Pol) ζ performs a crucial role in translesion synthesis (TLS). In yeast and cancer cells, Rev1 functions as an indispensable scaffolding component of Polζ and it imposes highly error-prone TLS upon Polζ. However, fo...
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| Publicat a: | Life Sci Alliance |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Life Science Alliance LLC
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7898466/ https://ncbi.nlm.nih.gov/pubmed/33514655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000900 |
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