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A novel role of DNA polymerase λ in translesion synthesis in conjunction with DNA polymerase ζ

By extending synthesis opposite from a diverse array of DNA lesions, DNA polymerase (Pol) ζ performs a crucial role in translesion synthesis (TLS). In yeast and cancer cells, Rev1 functions as an indispensable scaffolding component of Polζ and it imposes highly error-prone TLS upon Polζ. However, fo...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Yoon, Jung-Hoon, Basu, Debashree, Sellamuthu, Karthi, Johnson, Robert E, Prakash, Satya, Prakash, Louise
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898466/
https://ncbi.nlm.nih.gov/pubmed/33514655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000900
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