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Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5
The chemokine receptor CCR5 plays a vital role in immune surveillance and inflammation. However, molecular details that govern its endogenous chemokine recognition and receptor activation remain elusive. Here we report three cryo-electron microscopy structures of G(i1) protein-coupled CCR5 in a liga...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8260604/ https://ncbi.nlm.nih.gov/pubmed/34230484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24438-5 |
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