Disruptive Selection of Human Immunostimulatory and Immunosuppressive Genes Both Provokes and Prevents Rheumatoid Arthritis, Respectively, as a Self-Domestication Syndrome

Using our previously published Web service SNP_TATA_Comparator, we conducted a genome-wide study of single-nucleotide polymorphisms (SNPs) within core promoters of 68 human rheumatoid arthritis (RA)-related genes. Using 603 SNPs within 25 genes clinically associated with RA-comorbid disorders, we pr...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Klimova, Natalya V., Oshchepkova, Evgeniya, Chadaeva, Irina, Sharypova, Ekaterina, Ponomarenko, Petr, Drachkova, Irina, Rasskazov, Dmitry, Oshchepkov, Dmitry, Ponomarenko, Mikhail, Savinkova, Ludmila, Kolchanov, Nikolay A., Kozlov, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259950/
https://ncbi.nlm.nih.gov/pubmed/34239535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.610774
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