Candidate SNP Markers of Atherogenesis Significantly Shifting the Affinity of TATA-Binding Protein for Human Gene Promoters Show Stabilizing Natural Selection as a Sum of Neutral Drift Accelerating Atherogenesis and Directional Natural Selection Slowing It

(1) Background: The World Health Organization (WHO) regards atherosclerosis-related myocardial infarction and stroke as the main causes of death in humans. Susceptibility to atherogenesis-associated diseases is caused by single-nucleotide polymorphisms (SNPs). (2) Methods: Using our previously devel...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Ponomarenko, Mikhail, Rasskazov, Dmitry, Chadaeva, Irina, Sharypova, Ekaterina, Drachkova, Irina, Oshchepkov, Dmitry, Ponomarenko, Petr, Savinkova, Ludmila, Oshchepkova, Evgeniya, Nazarenko, Maria, Kolchanov, Nikolay
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037642/
https://ncbi.nlm.nih.gov/pubmed/32033288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21031045
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