Candidate SNP Markers of Familial and Sporadic Alzheimer's Diseases Are Predicted by a Significant Change in the Affinity of TATA-Binding Protein for Human Gene Promoters

While year after year, conditions, quality, and duration of human lives have been improving due to the progress in science, technology, education, and medicine, only eight diseases have been increasing in prevalence and shortening human lives because of premature deaths according to the retrospectiv...

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Main Authors: Petr Ponomarenko, Irina Chadaeva, Dmitry A. Rasskazov, Ekaterina Sharypova, Elena V. Kashina, Irina Drachkova, Dmitry Zhechev, Mikhail P. Ponomarenko, Ludmila K. Savinkova, Nikolay Kolchanov
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017-07-01
Colecção:Frontiers in Aging Neuroscience
Assuntos:
gene
promoter
TATA-binding protein
TBP-binding site
single nucleotide polymorphism
expression change
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00231/full
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