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Identification and initial characterization of a potent inhibitor of ferroptosis
Ferroptosis is a form of iron-dependent cell death characterized by elevated lipid peroxides and reactive oxygen species (ROS). Glutathione (GSH) plays an essential role in scavenging ROS to maintain cell viability, and acts as a cofactor of GSH peroxidase 4 (GPX4) that protects lipids from oxidatio...
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| Vydáno v: | J Cell Biochem |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8259732/ https://ncbi.nlm.nih.gov/pubmed/33377232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.29870 |
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