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Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors
The aquaglyceroporins are a subfamily of aquaporins that conduct both water and glycerol. Aquaporin-3 (AQP3) has an important physiological function in renal water reabsorption, and AQP3-mediated hydrogen peroxide (H(2)O(2)) permeability can enhance cytokine signaling in several cell types. The rela...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6509502/ https://ncbi.nlm.nih.gov/pubmed/30862673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006083 |
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