Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors

The aquaglyceroporins are a subfamily of aquaporins that conduct both water and glycerol. Aquaporin-3 (AQP3) has an important physiological function in renal water reabsorption, and AQP3-mediated hydrogen peroxide (H(2)O(2)) permeability can enhance cytokine signaling in several cell types. The rela...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Sonntag, Yonathan, Gena, Patrizia, Maggio, Anna, Singh, Tania, Artner, Isabella, Oklinski, Michal K., Johanson, Urban, Kjellbom, Per, Nieland, John Dirk, Nielsen, Søren, Calamita, Giuseppe, Rützler, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
Soggetti:
Methods and Resources
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509502/
https://ncbi.nlm.nih.gov/pubmed/30862673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006083
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