Aquaporin-9 Protein Is the Primary Route of Hepatocyte Glycerol Uptake for Glycerol Gluconeogenesis in Mice

It has been hypothesized that aquaporin-9 (AQP9) is part of the unknown route of hepatocyte glycerol uptake. In a previous study, leptin receptor-deficient wild-type mice became diabetic and suffered from fasting hyperglycemia whereas isogenic AQP9(−/−) knock-out mice remained normoglycemic. The rea...

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Detalhes bibliográficos
Main Authors: Jelen, Sabina, Wacker, Sören, Aponte-Santamaría, Camilo, Skott, Martin, Rojek, Aleksandra, Johanson, Urban, Kjellbom, Per, Nielsen, Søren, de Groot, Bert L., Rützler, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247941/
https://ncbi.nlm.nih.gov/pubmed/22081610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.297002
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