A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis

[Image: see text] Discovering compounds and mechanisms for inhibiting ferroptosis, a form of regulated, nonapoptotic cell death, has been of great interest in recent years. In this study, we demonstrate the ability of XJB-5-131, JP4-039, and other nitroxide-based lipid peroxidation mitigators to pre...

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Detaylı Bibliyografya
Yayımlandı:ACS Cent Sci
Asıl Yazarlar: Krainz, Tanja, Gaschler, Michael M., Lim, Chaemin, Sacher, Joshua R., Stockwell, Brent R., Wipf, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2016
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043442/
https://ncbi.nlm.nih.gov/pubmed/27725964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00199
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