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Transcriptional mechanisms of pancreatic β-cell maturation and functional adaptation
Pancreatic β-cells secrete insulin commensurate to circulating nutrient levels to maintain normoglycemia. The ability of β-cells to couple insulin secretion to nutrient stimuli is acquired during a postnatal maturation process. In mature β-cells the insulin secretory response adapts to changes in nu...
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| Опубликовано в: : | Trends Endocrinol Metab |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8259463/ https://ncbi.nlm.nih.gov/pubmed/34030925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2021.04.011 |
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