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Transcriptional mechanisms of pancreatic β-cell maturation and functional adaptation

Pancreatic β-cells secrete insulin commensurate to circulating nutrient levels to maintain normoglycemia. The ability of β-cells to couple insulin secretion to nutrient stimuli is acquired during a postnatal maturation process. In mature β-cells the insulin secretory response adapts to changes in nu...

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Detalhes bibliográficos
Publicado no:Trends Endocrinol Metab
Main Authors: Wortham, Matthew, Sander, Maike
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259463/
https://ncbi.nlm.nih.gov/pubmed/34030925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2021.04.011
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