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Mechanisms of β-cell functional adaptation to changes in workload

Insulin secretion must be tightly coupled to nutritional state to maintain blood glucose homeostasis. To this end, pancreatic β-cells sense and respond to changes in metabolic conditions, thereby anticipating insulin demands for a given physiological context. This is achieved in part through adjustm...

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Detalhes bibliográficos
Publicado no:Diabetes Obes Metab
Main Authors: Wortham, Matthew, Sander, Maike
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021190/
https://ncbi.nlm.nih.gov/pubmed/27615135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.12729
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