Effect of Malnutrition on the Pharmacokinetics of Anti-tuberculosis Drugs in Ghanaian Children

BACKGROUND: Antituberculosis (anti-TB) drugs dosing based on only weight may contribute to suboptimal drug concentrations and poor treatment outcomes in malnourished children. We examined the effect of malnutritional state on pharmacokinetics (PK) of the first-line anti-TB drugs in children. METHODS...

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Publicado en:Int J Tuberc Lung Dis
Main Authors: Hagan Seneadza, Nana Ayegua, Antwi, Sampson, Yang, Hongmei, Enimil, Anthony, Dompreh, Albert, Wiesner, Lubbe, Peloquin, Charles A, Lartey, Margaret, Lauzardo, Michael, Kwara, Awewura
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259402/
https://ncbi.nlm.nih.gov/pubmed/33384043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5588/ijtld.20.0301
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