Evaluation of the Adequacy of WHO Revised Dosages of the First-Line Antituberculosis Drugs in Children with Tuberculosis Using Population Pharmacokinetic Modeling and Simulations

Optimal doses for antituberculosis (anti-TB) drugs in children have yet to be established. In 2010, the World Health Organization (WHO) recommended revised dosages of the first-line anti-TB drugs for children. Pharmacokinetic (PK) studies that investigated the adequacy of the WHO revised dosages to...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Horita, Yasuhiro, Alsultan, Abdullah, Kwara, Awewura, Antwi, Sampson, Enimil, Antony, Ortsin, Antoinette, Dompreh, Albert, Yang, Hongmei, Wiesner, Lubbe, Peloquin, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125554/
https://ncbi.nlm.nih.gov/pubmed/29914960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00008-18
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