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High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity
Obesity is an established risk factor for cancer in many tissues. In the mammalian intestine, a pro-obesity high-fat diet (HFD) promotes regeneration and tumorigenesis by enhancing intestinal stem cell (ISC) numbers, proliferation, and function. Although PPAR (peroxisome proliferator-activated recep...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8258630/ https://ncbi.nlm.nih.gov/pubmed/34107251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109212 |
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