High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity

Obesity is an established risk factor for cancer in many tissues. In the mammalian intestine, a pro-obesity high-fat diet (HFD) promotes regeneration and tumorigenesis by enhancing intestinal stem cell (ISC) numbers, proliferation, and function. Although PPAR (peroxisome proliferator-activated recep...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Mana, Miyeko D., Hussey, Amanda M., Tzouanas, Constantine N., Imada, Shinya, Millan, Yesenia Barrera, Bahceci, Dorukhan, Saiz, Dominic R., Webb, Anna T., Lewis, Caroline A., Carmeliet, Peter, Mihaylova, Maria M., Shalek, Alex K., Yilmaz, Ömer H.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258630/
https://ncbi.nlm.nih.gov/pubmed/34107251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109212
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars