High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity

Obesity is an established risk factor for cancer in many tissues. In the mammalian intestine, a pro-obesity high-fat diet (HFD) promotes regeneration and tumorigenesis by enhancing intestinal stem cell (ISC) numbers, proliferation, and function. Although PPAR (peroxisome proliferator-activated recep...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Mana, Miyeko D., Hussey, Amanda M., Tzouanas, Constantine N., Imada, Shinya, Millan, Yesenia Barrera, Bahceci, Dorukhan, Saiz, Dominic R., Webb, Anna T., Lewis, Caroline A., Carmeliet, Peter, Mihaylova, Maria M., Shalek, Alex K., Yilmaz, Ömer H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8258630/
https://ncbi.nlm.nih.gov/pubmed/34107251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109212
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