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FBXL6 degrades phosphorylated p53 to promote tumor growth

The ubiquitin-proteasome system regulates many distinct biological processes. Its dysregulation causes various diseases, including but not limited to cancer. In this study, based on the analysis of gene expression in several colorectal cancer (CRC) datasets, we show that FBXL6, a poorly-characterize...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Li, Yajun, Cui, Kaisa, Zhang, Qiang, Li, Xu, Lin, Xingrong, Tang, Yi, Prochownik, Edward V., Li, Youjun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257708/
https://ncbi.nlm.nih.gov/pubmed/33568778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-021-00739-6
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