MicroRNA-148a deficiency promotes hepatic lipid metabolism and hepatocarcinogenesis in mice

miRNAs are involved in many physiologic and disease processes by virtue of degrading specific mRNAs or inhibiting their translation. miR-148a has been implicated in the control of tumor growth and cholesterol and triglyceride homeostasis using in vitro or in vivo gene expression- and silencing-based...

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Publicat a:Cell Death Dis
Autors principals: Cheng, Li, Zhu, Yahui, Han, Han, Zhang, Qiang, Cui, Kaisa, Shen, Hongxing, Zhang, Jinxiang, Yan, Jun, Prochownik, Edward, Li, Youjun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550856/
https://ncbi.nlm.nih.gov/pubmed/28703810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.309
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