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The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth

Deubiquitinases (DUBs) play essential roles in normal cell proliferation and tumor growth. However, the molecular mechanisms of DUBs on hepatocellular carcinoma (HCC) remains largely unknown. In this study, based on analysis of several HCC datasets, we found that the USP21 gene, which encodes a memb...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Li, Wenjuan, Cui, Kaisa, Prochownik, Edward V, Li, Youjun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924753/
https://ncbi.nlm.nih.gov/pubmed/29706623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0523-z
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