Zfp57 inactivation illustrates the role of ICR methylation in imprinted gene expression during neural differentiation of mouse ESCs

ZFP57 is required to maintain the germline-marked differential methylation at imprinting control regions (ICRs) in mouse embryonic stem cells (ESCs). Although DNA methylation has a key role in genomic imprinting, several imprinted genes are controlled by different mechanisms, and a comprehensive stu...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Acurzio, Basilia, Verma, Ankit, Polito, Alessia, Giaccari, Carlo, Cecere, Francesco, Fioriniello, Salvatore, Della Ragione, Floriana, Fico, Annalisa, Cerrato, Flavia, Angelini, Claudia, Feil, Robert, Riccio, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257706/
https://ncbi.nlm.nih.gov/pubmed/34226608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93297-3
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