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Is ZFP57 binding to H19/IGF2:IG-DMR affected in Silver-Russell syndrome?

BACKGROUND: Loss of paternal methylation (LOM) of the H19/IGF2 intergenic differentially methylated region (H19/IGF2:IG-DMR) causes alteration of H19/IGF2 imprinting and Silver-Russell syndrome (SRS). Recently, internal deletions of the H19/IGF2:IG-DMR have been associated with LOM and SRS when pres...

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Publicado en:Clin Epigenetics
Autores principales: Sparago, Angela, Cerrato, Flavia, Riccio, Andrea
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822596/
https://ncbi.nlm.nih.gov/pubmed/29484033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0454-7
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