ZFP57 dictates allelic expression switch of target imprinted genes

ZFP57 is a master regulator of genomic imprinting. It has both maternal and zygotic functions that are partially redundant in maintaining DNA methylation at some imprinting control regions (ICRs). In this study, we found that DNA methylation was lost at most known ICRs in Zfp57 mutant embryos. Furth...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jiang, Weijun, Shi, Jiajia, Zhao, Jingjie, Wang, Qiu, Cong, Dan, Chen, Fenghua, Zhang, Yu, Liu, Yuhan, Zhao, Junzheng, Chen, Qian, Gu, Linhao, Zhou, Wenjia, Wang, Chenhang, Fang, Zhaoyuan, Geng, Shuhui, Xie, Wei, Chen, Luo-Nan, Yang, Yang, Bai, Yun, Lin, Haodong, Li, Xiajun
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865185/
https://ncbi.nlm.nih.gov/pubmed/33500348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005377118
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