ZFP57 dictates allelic expression switch of target imprinted genes

ZFP57 is a master regulator of genomic imprinting. It has both maternal and zygotic functions that are partially redundant in maintaining DNA methylation at some imprinting control regions (ICRs). In this study, we found that DNA methylation was lost at most known ICRs in Zfp57 mutant embryos. Furth...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Jiang, Weijun, Shi, Jiajia, Zhao, Jingjie, Wang, Qiu, Cong, Dan, Chen, Fenghua, Zhang, Yu, Liu, Yuhan, Zhao, Junzheng, Chen, Qian, Gu, Linhao, Zhou, Wenjia, Wang, Chenhang, Fang, Zhaoyuan, Geng, Shuhui, Xie, Wei, Chen, Luo-Nan, Yang, Yang, Bai, Yun, Lin, Haodong, Li, Xiajun
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2021
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865185/
https://ncbi.nlm.nih.gov/pubmed/33500348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005377118
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