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ZFP57 dictates allelic expression switch of target imprinted genes
ZFP57 is a master regulator of genomic imprinting. It has both maternal and zygotic functions that are partially redundant in maintaining DNA methylation at some imprinting control regions (ICRs). In this study, we found that DNA methylation was lost at most known ICRs in Zfp57 mutant embryos. Furth...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7865185/ https://ncbi.nlm.nih.gov/pubmed/33500348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005377118 |
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