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ZFP57 maintains the parent-of-origin-specific expression of the imprinted genes and differentially affects non-imprinted targets in mouse embryonic stem cells
ZFP57 is necessary for maintaining repressive epigenetic modifications at Imprinting control regions (ICRs). In mouse embryonic stem cells (ESCs), ZFP57 binds ICRs (ICR(BS)) and many other loci (non-ICR(BS)). To address the role of ZFP57 on all its target sites, we performed high-throughput and mult...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5041456/ https://ncbi.nlm.nih.gov/pubmed/27257070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw505 |
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