ZFP57 maintains the parent-of-origin-specific expression of the imprinted genes and differentially affects non-imprinted targets in mouse embryonic stem cells

ZFP57 is necessary for maintaining repressive epigenetic modifications at Imprinting control regions (ICRs). In mouse embryonic stem cells (ESCs), ZFP57 binds ICRs (ICR(BS)) and many other loci (non-ICR(BS)). To address the role of ZFP57 on all its target sites, we performed high-throughput and mult...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Riso, Vincenzo, Cammisa, Marco, Kukreja, Harpreet, Anvar, Zahra, Verde, Gaetano, Sparago, Angela, Acurzio, Basilia, Lad, Shraddha, Lonardo, Enza, Sankar, Aditya, Helin, Kristian, Feil, Robert, Fico, Annalisa, Angelini, Claudia, Grimaldi, Giovanna, Riccio, Andrea
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Gene regulation, Chromatin and Epigenetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041456/
https://ncbi.nlm.nih.gov/pubmed/27257070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw505
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