Both Epimutations and Chromosome Aberrations Affect Multiple Imprinted Loci in Aggressive Wilms Tumors

SIMPLE SUMMARY: About 7% of all children’s malignancies are represented by the embryonal renal cancer Wilms tumor (WT). Since methylation imprinting alterations at multiple loci dictated by chromosome copy-number variations have been recently demonstrated in adult cancers, we investigated the presen...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Pignata, Laura, Palumbo, Orazio, Cerrato, Flavia, Acurzio, Basilia, de Álava, Enrique, Roma, Josep, Gallego, Soledad, Mora, Jaume, Carella, Massimo, Riccio, Andrea, Verde, Gaetano
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698742/
https://ncbi.nlm.nih.gov/pubmed/33217932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113411
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