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Importance of WNT-dependent signaling for derivation and maintenance of primed pluripotent bovine embryonic stem cells
The WNT signaling system plays an important but paradoxical role in the regulation of pluripotency. In the cow, IWR-1, which inhibits canonical WNT activation and has WNT-independent actions, promotes the derivation of primed pluripotent embryonic stem cells from the blastocyst. Here, we describe a...
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| Yayımlandı: | Biol Reprod |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8256100/ https://ncbi.nlm.nih.gov/pubmed/33899086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioab075 |
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