Importance of WNT-dependent signaling for derivation and maintenance of primed pluripotent bovine embryonic stem cells

The WNT signaling system plays an important but paradoxical role in the regulation of pluripotency. In the cow, IWR-1, which inhibits canonical WNT activation and has WNT-independent actions, promotes the derivation of primed pluripotent embryonic stem cells from the blastocyst. Here, we describe a...

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Detalhes bibliográficos
Publicado no:Biol Reprod
Main Authors: Xiao, Yao, Amaral, Thiago F, Ross, Pablo J, Soto, Delia A, Diffenderfer, Kenneth E, Pankonin, Aimee R, Jeensuk, Surawich, Tríbulo, Paula, Hansen, Peter J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256100/
https://ncbi.nlm.nih.gov/pubmed/33899086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioab075
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