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Importance of WNT-dependent signaling for derivation and maintenance of primed pluripotent bovine embryonic stem cells

The WNT signaling system plays an important but paradoxical role in the regulation of pluripotency. In the cow, IWR-1, which inhibits canonical WNT activation and has WNT-independent actions, promotes the derivation of primed pluripotent embryonic stem cells from the blastocyst. Here, we describe a...

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Detaylı Bibliyografya
Yayımlandı:Biol Reprod
Asıl Yazarlar: Xiao, Yao, Amaral, Thiago F, Ross, Pablo J, Soto, Delia A, Diffenderfer, Kenneth E, Pankonin, Aimee R, Jeensuk, Surawich, Tríbulo, Paula, Hansen, Peter J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8256100/
https://ncbi.nlm.nih.gov/pubmed/33899086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioab075
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