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The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells

WNT signaling is involved in maintaining stem cells in an undifferentiated state; however, it is often unclear which WNTs and WNT receptors are mediating these activities. Here we examined the role of the WNT receptor FZD7 in maintaining human embryonic stem cells (hESCs) in an undifferentiated and...

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Detalhes bibliográficos
Main Authors: Fernandez, Antonio, Huggins, Ian J., Perna, Luca, Brafman, David, Lu, Desheng, Yao, Shiyin, Gaasterland, Terry, Carson, Dennis A., Willert, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910637/
https://ncbi.nlm.nih.gov/pubmed/24474766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323697111
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