Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells

WNT proteins are secreted symmetry breaking signals that interact with cell surface receptors of the FZD family to regulate a multitude of developmental processes. Studying selectivity between WNTs and FZDs has been hampered by the paucity of purified WNT proteins and by their apparent non-selective...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Gumber, Diana, Do, Myan, Suresh Kumar, Neya, Sonavane, Pooja R, Wu, Christina C N, Cruz, Luisjesus S, Grainger, Stephanie, Carson, Dennis, Gaasterland, Terry, Willert, Karl
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2020
Gaiak:
Developmental Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759383/
https://ncbi.nlm.nih.gov/pubmed/33331818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63060
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