A transcribed enhancer dictates mesendoderm specification in pluripotency

Enhancers and long noncoding RNAs (lncRNAs) are key determinants of lineage specification during development. Here, we evaluate remodeling of the enhancer landscape and modulation of the lncRNA transcriptome during mesendoderm specification. We sort mesendodermal progenitors from differentiating emb...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Alexanian, Michael, Maric, Daniel, Jenkinson, Stephen P., Mina, Marco, Friedman, Clayton E., Ting, Ching-Chia, Micheletti, Rudi, Plaisance, Isabelle, Nemir, Mohamed, Maison, Damien, Kernen, Jasmin, Pezzuto, Iole, Villeneuve, Dominic, Burdet, Frédéric, Ibberson, Mark, Leib, Stephen L., Palpant, Nathan J., Hernandez, Nouria, Ounzain, Samir, Pedrazzini, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703900/
https://ncbi.nlm.nih.gov/pubmed/29180618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01804-w
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