Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause

The epiblast, which provides the foundation of the future body, is actively reshaped during early embryogenesis, but the reshaping mechanisms are poorly understood. Here, using a 3D in vitro model of early epiblast development, we identify the canonical Wnt/β-catenin pathway and its central downstre...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Fan, Rui, Kim, Yung Su, Wu, Jie, Chen, Rui, Zeuschner, Dagmar, Mildner, Karina, Adachi, Kenjiro, Wu, Guangming, Galatidou, Styliani, Li, Jianhua, Schöler, Hans R., Leidel, Sebastian A., Bedzhov, Ivan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603494/
https://ncbi.nlm.nih.gov/pubmed/33127892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19353-0
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