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Maintaining embryonic stem cell pluripotency with Wnt signaling

Wnt signaling pathways control lineage specification in vertebrate embryos and regulate pluripotency in embryonic stem (ES) cells, but how the balance between progenitor self-renewal and differentiation is achieved during axis specification and tissue patterning remains highly controversial. The con...

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Bibliographic Details
Main Author: Sokol, Sergei Y.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177306/
https://ncbi.nlm.nih.gov/pubmed/21903672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.066209
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