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Mechanisms maintaining genomic integrity in embryonic stem cells and induced pluripotent stem cells

Embryonic stem cells (ESCs) are pluripotent, self-renewing cells that are isolated during the blastocyst stage of embryonic development. Whether these cells are derived from humans, mice, or other organisms, all ESCs must employ mechanisms that prevent the propagation of mutations, generated as a co...

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Detalhes bibliográficos
Autor principal: Tichy, Elisia D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077782/
https://ncbi.nlm.nih.gov/pubmed/21768163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1258/ebm.2011.011107
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