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Mechanisms maintaining genomic integrity in embryonic stem cells and induced pluripotent stem cells

Embryonic stem cells (ESCs) are pluripotent, self-renewing cells that are isolated during the blastocyst stage of embryonic development. Whether these cells are derived from humans, mice, or other organisms, all ESCs must employ mechanisms that prevent the propagation of mutations, generated as a co...

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Bibliografski detalji
Glavni autor: Tichy, Elisia D.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077782/
https://ncbi.nlm.nih.gov/pubmed/21768163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1258/ebm.2011.011107
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