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Restoration of Cavernous Veno-Occlusive Function through Chronic Administration of a Jun-Amino Terminal Kinase Inhibitor and a LIM-Kinase 2 Inhibitor by Suppressing Cavernous Apoptosis and Fibrosis in a Rat Model of Cavernous Nerve Injury: A Comparison with a Phosphodiesterase Type 5 Inhibitor

PURPOSE: To determine if chronic administration of Jun-amino terminal kinase (JNK)-inhibitors and LIM-kinase 2 (LIMK2)-inhibitors from the immediate post-injury period in a rat model of cavernous-nerve-crush-injury could normalize cavernous-veno-occlusive-function, and to compare it with phosphodies...

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Detalhes bibliográficos
Publicado no:World J Mens Health
Main Authors: Cho, Min Chul, Lee, Junghoon, Park, Juhyun, Kim, Soo Woong
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Sexual Medicine and Andrology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255392/
https://ncbi.nlm.nih.gov/pubmed/32777863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5534/wjmh.200085
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